An improved synthesis of 3,5‐disubstituted isoxazoles and pyrazoles from <i>C</i>(α),<i>O</i>‐dilithiooximes and <i>C</i>(α),<i>N</i>‐dilithiophenylhydrazones

Tammy D. Fulmer, Lisette P. Dasher, Bonni L. Bobb, Jana D. Wilson, Kimberly L. Sides, Charles F. Beam

Journal of Heterocyclic Chemistry · 1980 · 41 citations · 4 references

Concepts

Abstract

Abstract C (α), O ‐Dilithiooximes and C (α), N ‐dilithiophenylhydrazones were prepared using an excess of lithium diisopropylamide (1:3). Condensation with esters followed by acid cyclization gave isoxazoles and pyrazoles.

References

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