Identification of drugs subtype-selective for α2A-, α2B-, and α2C-adrenoceptors in the pig cerebellum and kidney cortex

Delineation of rat kidney α2A- and α2B-adrenoeeptors with [3H]RX821002 radiollgand binding: computer modelling reveals that guanfacine is an α2A-selective compound

Staffan Uhlén, Jarl E. S. Wikberg · European Journal of Pharmacology · 1991 · 142 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Discrimination and pharmacological characterization of I2-imidazoline sites with [3H]idazoxan and alpha-2 adrenoceptors with [3H]RX821002 (2-methoxy idazoxan) in the human and rat brains.

Antonio Miralles, Gabriel Olmos, Magdalena Sastre et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 139 citations

Medicine, Neurobiology, Pharmacology +9

Characterization of the alpha-2C adrenergic receptor subtype in the opossum kidney and in the OK cell line.

Howard S. Blaxall, T J Murphy, J C Baker et al. · Journal of Pharmacology and Experimental Therapeutics · 1991 · 116 citations · Full text

Medicine, Pharmacology, Cellular Pharmacology +9

Cloning, sequencing, and expression of the gene encoding the porcine alpha 2-adrenergic receptor. Allosteric modulation by Na+, H+, and amiloride analogs.

Cheryl A. Guyer, Debra A. Horstman, Amy L. Wilson et al. · Journal of Biological Chemistry · 1990 · 116 citations · Full text

Medicine, Biochemistry, Pharmacology +11

Pharmacological characterization of rat alpha 2-adrenergic receptors.

Jeffrey K. Harrison, Danila d’Angelo, Dewan Zeng et al. · Molecular Pharmacology · 1991 · 113 citations

Medicine, Molecular Biology, Pharmacology +17