Immunohistochemical expression of the c-kit proto-oncogene product in human malignant and non-malignant breast tissues

Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the SId mutant

John G. Flanagan, David C. Chan, Philip Leder · Cell · 1991 · 733 citations

Life Sciences, Genetics, Molecular Biology +11

Primary structure of c‐kit: relationship with the CSF‐1/PDGF receptor kinase family–oncogenic activation of v‐kit involves deletion of extracellular domain and C terminus.

Fei-Hua Qiu, Partha Ray, Kate Brown et al. · The EMBO Journal · 1988 · 718 citations · Full text

Life Sciences, Molecular Biology, Oncology +13

Embryonic RNA expression patterns of the c‐kit receptor and its cognate ligand suggest multiple functional roles in mouse development.

Eli Keshet, Stewart D. Lyman, DE Williams et al. · The EMBO Journal · 1991 · 344 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +15

Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase.

Alastair D. Reith, Christine Ellis, Stewart D. Lyman et al. · The EMBO Journal · 1991 · 265 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Progression of human cutaneous melanoma is associated with loss of expression of c<i>‐kit</i> proto‐oncogene receptor

Pier Giorgio Natali, M. Nicotra, Almut Winkler et al. · International Journal of Cancer · 1992 · 208 citations

Medicine, Dermatology, Oncology +17