RANKL Upregulation Associated With Periodontitis and <i>Porphyromonas gingivalis</i>

Abstract

Chronic periodontitis was associated with RANKL mRNA upregulation and increased RANKL/OPG mRNA expression ratio. In addition, our data showed for the first time to our knowledge an association between upregulated RANKL levels and the number of P. gingivalis in clinically obtained periodontal tissues.