A Defect in Nurturing in Mice Lacking the Immediate Early Gene fosB

Genomic sequencing.

George M. Church, W Gilbert · Proceedings of the National Academy of Sciences · 1984 · 8.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

En Li, Timothy H. Bestor, Rudolf Jaenisch · Cell · 1992 · 4K citations

Life Sciences, Genetics, Molecular Biology +14

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

Medicine, Genetics, Molecular Genetics +15

Simplified mammalian DNA isolation procedure

Peter W. Laird, Alice Zijderveld, Koert Linders et al. · Nucleic Acids Research · 1991 · 1.5K citations · Full text

Life Sciences, Biology, Molecular Biology +8

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

Tom Curran · Proceedings of the National Academy of Sciences · 1991 · 1.3K citations

Life Sciences, Genetics, Molecular Biology +14