Enzymatic amplification and molecular cloning of cDNA encoding the small and large subunits of bovine interleukin 12

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.

Roberto Manetti, Paola Parronchi, M G Giudizi et al. · The Journal of Experimental Medicine · 1993 · 1.7K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Recombinant IL-12 administration induces tumor regression in association with IFN- <i>gamma</i> production.

Chet Nastala, Howard Edington, T G McKinney et al. · The Journal of Immunology · 1994 · 792 citations · Full text

Life Sciences, Immunology, Oncology +17

Cloning and expression of murine IL-12

David S. Schoenhaut, A O Chua, A G Wolitzky et al. · The Journal of Immunology · 1992 · 469 citations

Life Sciences, Cell Biology, Immunology +10

Synergy between recombinant interleukin 2 (rIL 2) and IL 2-depleted lymphokine-containing supernatants in facilitating allogeneic human cytolytic T lymphocyte responses in vitro.

Maurice K. Gately, Darien E. Wilson, H.L.S. Wong · The Journal of Immunology · 1986 · 69 citations · Full text

Life Sciences, Cancer Biology, Immunology +11

Characterization of a factor(s) which synergizes with recombinant interleukin 2 in promoting allogeneic human cytolytic T-lymphocyte responses in vitro

H.L.S. Wong, Darien E. Wilson, James C. Jenson et al. · Cellular Immunology · 1988 · 59 citations

Life Sciences, Immunology, Cellular Immunology +13