Polysaccharide nanogel delivery of a TNF-α and RANKL antagonist peptide allows systemic prevention of bone loss

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Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density

W. Scott Simonet, Dave Lacey, Colin R. Dunstan et al. · Cell · 1997 · 5.1K citations · Full text

Medicine, Biochemistry, Molecular Biology +13

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

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Medicine, Cell Biology, Genetics +17

Self-aggregates of hydrophobized polysaccharides in water. Formation and characteristics of nanoparticles

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Pharmacy, Biochemistry, Materials Science +17

Self-assembled hydrogel nanoparticle of cholesterol-bearing pullulan as a carrier of protein drugs: Complexation and stabilization of insulin

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Pharmacy, Biochemistry, Pharmaceutics +16