Contribution of the Interleukin 4 Gene to Susceptibility to Subacute Sclerosing Panencephalitis

Abstract

To our knowledge, this study is the first to demonstrate the possibility that the IL-4 promoter gene -589 T gene polymorphism with increased IL-4 synthesis in combination with IRF-1 allele 1 confers host genetic susceptibility to SSPE in Japanese subjects.