Toshiro Hara

Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome

Yoshiyuki Minegishi, Masako Saitō, Shigeru Tsuchiya et al. · Nature · 2007 · 1K citations

Life Sciences, Genetics, Immunology +13

Efficacy of immunoglobulin plus prednisolone for prevention of coronary artery abnormalities in severe Kawasaki disease (RAISE study): a randomised, open-label, blinded-endpoints trial

Tohru Kobayashi, Tsutomu Saji, Tetsuya Otani et al. · The Lancet · 2012 · 674 citations

Medicine, Cardiology, Pharmacotherapy +11

Selective predisposition to bacterial infections in IRAK-4–deficient children: IRAK-4–dependent TLRs are otherwise redundant in protective immunity

Cheng‐Lung Ku, Horst von Bernuth, Capucine Pïcard et al. · The Journal of Experimental Medicine · 2007 · 392 citations · Full text

Life Sciences, Immunology, Microbiology +17

SAMD9 mutations cause a novel multisystem disorder, MIRAGE syndrome, and are associated with loss of chromosome 7

Satoshi Narumi, Naoko Amano, Tomohiro Ishii et al. · Nature Genetics · 2016 · 333 citations

Life Sciences, Genetics, Molecular Genetics +11

Smad2 and Smad3 Are Redundantly Essential for the TGF-β–Mediated Regulation of Regulatory T Plasticity and Th1 Development

Tomohito Takimoto, Yu Wakabayashi, Takashi Sekiya et al. · The Journal of Immunology · 2010 · 325 citations · Full text

Life Sciences, Developmental Biology, Immunology +17