Concepedia

Site-directed antisense oligonucleotide decreases the expression of amyloid precursor protein and reverses deficits in learning and memory in aged SAMP8 mice

Vijaya B. Kumar, Susan A. Farr, James F. Flood, Vyas Kamlesh, Mark Franko, William A. Banks, John E. Morley

Peptides · 2000 · 195 citations · 31 references

DOI

Concepts

References

31

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

George G. Glenner, Caine W. Wong · Biochemical and Biophysical Research Communications · 1984 · 5.4K citations

, , +14

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Karen Hsiao, Paul F. Chapman, Steven P. Nilsen et al. · Science · 1996 · 4.2K citations

, , +17

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Dale Schenk, Robin Barbour, Whitney Dunn et al. · Nature · 1999 · 3.2K citations

, , +14

Correlation Between Elevated Levels of Amyloid β-Peptide in the Brain and Cognitive Decline

Jan Näslund · JAMA · 2000 · 1.3K citations

, , +12

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum.

Nelson Arispe, E Rojas, Harvey B. Pollard · Proceedings of the National Academy of Sciences · 1993 · 928 citations

, , +17