Promoter-independent activation of heterologous virus gene expression by the herpes simplex virus immediate-early protein ICP27

High efficiency gene transfer into mammalian cells

Cornelia M. Gorman, David P. Lane, Peter Rigby · Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 1984 · 490 citations

Gene Therapies, Xenotransplantation, Developmental Biology +15

Herpes simplex virus type 1 ICP27 is an essential regulatory protein

Wendy R. Sacks, C C Greene, Doris P. Aschman et al. · Journal of Virology · 1985 · 432 citations · Full text

Viral Replication, Immunology, Viral Pathogenesis +19

Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed-early promoters

Peter O’Hare, Gary S. Hayward · Journal of Virology · 1985 · 344 citations · Full text

Viral Replication, Delayed-early Promoters, Genetics +16

Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient

Ann Marie McCarthy, Linda McMahan, Priscilla A. Schaffer · Journal of Virology · 1989 · 331 citations · Full text

Viral Replication, Genetics, Viral Polymerase Mechanism +16

Complete DNA sequence of the short repeat region in the genome of herpes simplex virus type 1

Duncan J. McGeoch, Aidan Dolan, Sally Donald et al. · Nucleic Acids Research · 1986 · 331 citations · Full text