Concepedia

A second generation MRI contrast agent for imaging zinc ions in vivo

Luis M. De Leon Rodriguez, Angelo Josue M. Lubag, Jorge A. López, Gabriel Andreu-de-Riquer, José C. Alvarado‐Monzón, A. Dean Sherry

MedChemComm · 2012 · 32 citations · 10 references

DOIFull text

Open access

Abstract

A Zn<sup>2+</sup> specific GdDOTA derivative containing two bis-(3-pyrazolyl) units was prepared and characterized. Unlike a previously reported Zn<sup>2+</sup> binding agent, the new agent binds to human albumin both in the presence and absence of Zn<sup>2+</sup>.

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