Homozinniol, a New Phytotoxic Metabolite from <i>Alternaria solani</i>

Abstract

A bioassay-guided fractionation of the phytotoxic crude extract of Alternaria solani resulted in the isolation of two phytotoxic metabolites identified as zinniol (1) and a new polyketide: homozinniol (2). A third metabolite, 6-[(3‘,3‘-dimethylallyl)oxy]-4-methoxy-5-methylphthalide (3) was also isolated and identified. Structural assignment of the metabolites was based primarily on the analysis of their mass spectrometry and 1H NMR spectroscopy data. Keywords: Alternaria solani; Solanum tuberosum; Lycopersicon esculentum; phytotoxin; zinniol; homozinniol; polyketide; phthalide