Islet transplantation outcomes in mice are better with fresh islets and exendin-4 treatment

Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen

A.M. James Shapiro, Jonathan R.T. Lakey, Edmond A. Ryan et al. · New England Journal of Medicine · 2000 · 5.3K citations · Full text

Medicine, Endocrinology, Surgery +16

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.

Gang Xu, Doris A. Stoffers, Joel F. Habener et al. · Diabetes · 1999 · 1.2K citations

Life Sciences, Endocrinology, Physiology +16

Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol

Edmond A. Ryan, Jonathan R. T. Lakey, Ray V. Rajotte et al. · Diabetes · 2001 · 872 citations · Full text

Medicine, Endocrinology, Surgery +17

Glucagon-like Peptide-1 Receptor Signaling Modulates β Cell Apoptosis

Yazhou Li, Tanya Hansotia, Bernardo Yusta et al. · Journal of Biological Chemistry · 2002 · 590 citations · Full text

Life Sciences, Endocrinology, Pharmacology +17

Glucagon-Like Peptide-1 Promotes Islet Cell Growth and Inhibits Apoptosis in Zucker Diabetic Rats

Loredana Farilla, Hongxiang Hui, Elizabeth M. Kang et al. · Endocrinology · 2002 · 506 citations · Full text

Life Sciences, Endocrinology, Physiology +8