Synthetic Communications · 2011 · 10 citations · 8 references
Natural SciencesChemistryMedicinal ChemistryOrganic ChemistrySynthetic Medicinal ChemistryHeterocycle SynthesisHeterocyclic ChemistryMacrocycle SynthesisOrganic SynthesisRetrosynthetic AnalysisAsymmetric Heterocycle SynthesisAsymmetric SynthesisLactam Synthesis
Abstract In this article, we report a facile asymmetric synthesis of the pyrrolo[2,1-a]benzazepine ring system based around a stereoselective N-acyliminium cyclization of a novel chiral lactam template.
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Gary A. Flynn, Eugène L. Giroux, Richard C. Dage · Journal of the American Chemical Society · 1987 · 97 citations
Pharmacy, Chemistry, Pharmacology +13