Complete Freund’s adjuvant–induced acute inflammatory pain could be attenuated by triptolide via inhibiting spinal glia activation in rats

Ethical guidelines for investigations of experimental pain in conscious animals

M. Zimmermann · Pain · 1983 · 7.8K citations

Medicine, Anesthesiology, Animal Sciences +14

p38 Mitogen-Activated Protein Kinase Is Activated after a Spinal Nerve Ligation in Spinal Cord Microglia and Dorsal Root Ganglion Neurons and Contributes to the Generation of Neuropathic Pain

Shan‐Xue Jin, Zhi-Ye Zhuang, Clifford J. Woolf et al. · Journal of Neuroscience · 2003 · 861 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Interactions between the immune and nervous systems in pain

Ke Ren, Ronald Dubner · Nature Medicine · 2010 · 813 citations

Life Sciences, Immunology, Neuroscience +12

A cascade of cytokines mediates mechanical inflammatory hypernociception in mice

Thiago M. Cunha, Waldiceu A. Verri, João S. Silva et al. · Proceedings of the National Academy of Sciences · 2005 · 605 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding

Michael J. Iadarola, Linda S. Brady, Gaetano Draisci et al. · Pain · 1988 · 440 citations

Life Sciences, Neuroscience, Pharmacology +17