Suitability of the MTT-based cytotoxicity assay to detect okadaic acid contamination of mussels

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.

James Carmichael, William DeGraff, Adi F. Gazdar et al. · PubMed · 1987 · 3.8K citations

Medicine, Pharmacology, Chemotherapy +11

Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines.

Dominic A. Scudiero, Robert H. Shoemaker, Kenneth D. Paull et al. · PubMed · 1988 · 2.4K citations

Medicine, Oncology, Pharmacology +9

Okadaic acid, a cytotoxic polyether from two marine sponges of the genus Halichondria

Kazuo Tachibana, Paul J. Scheuer, Yasumasa Tsukitani et al. · Journal of the American Chemical Society · 1981 · 743 citations

Natural Sciences, Chemistry, Toxicology +12

Isolation and structure of yessotoxin, a novel polyether compound implicated in diarrhetic shellfish poisoning

Michio Murata, Masanori Kumagai, Jong‐Soo Lee et al. · Tetrahedron Letters · 1987 · 372 citations

Life Sciences, Pharmacology, Toxicology +14

The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cells

Roald Bøe, Bjørn Tore Gjertsen, Olav Karsten Vintermyr et al. · Experimental Cell Research · 1991 · 331 citations

Life Sciences, Biochemistry, Cell Biology +11