Concepedia

Time-dependent Cytotoxicity Testing

Time-Dependent Cytotoxicity Testing is a cytotoxicity evaluation method that systematically assesses the dynamic changes in cell viability or damage over multiple time points to distinguish transient from cumulative toxic effects induced by a substance.

198

Publications

9.5K

Citations

912

Authors

330

Institutions

Publications per year

2017–2026

61

Variants

Time-course Cytotoxicity Testing

Parents

Publications

198

A practical note on the use of cytotoxicity assays

Jörg Weyermann, Dirk Lochmann, Andreas Zimmer · International Journal of Pharmaceutics · 2004 · 516 citations

, , +9

Use of Multiple Assay Endpoints to Investigate the Effects of Incubation Time, Dose of Toxin, and Plating Density in Cell-Based Cytotoxicity Assays

Terry Riss, Richard A Moravec · Assay and Drug Development Technologies · 2004 · 365 citations

, , +16

Cytotoxicity test with simplified crystal violet staining method using microtitre plates and its application to injection drugs

Kyoko Saotome, Hiroshi Morita, Makoto Umeda · Toxicology in Vitro · 1989 · 263 citations

, , +10

Improved short- and long-term XTT-based colorimetric cellular cytotoxicity assay for melanoma and other tumor cells

L.M. Jost, John M. Kirkwood, Theresa L. Whiteside · Journal of Immunological Methods · 1992 · 186 citations

, , +10

Silver Nanoparticle-Induced Autophagic-Lysosomal Disruption and NLRP3-Inflammasome Activation in HepG2 Cells Is Size-Dependent

Anurag Mishra, Jiwen Zheng, Xing Tang et al. · Toxicological Sciences · 2016 · 183 citations · Full text

, , +17

1–5 of 198

Authors

912

  1. RH
    Richard H. Clothier

    University of Nottingham, United Kingdom

    4 publications · 309 citations

    4

    h-index

  2. MB
    Michael Balls

    University of Nottingham, United Kingdom

    4 publications · 301 citations

    4

    h-index

  3. TF
    Ting‐Jun Fan

    Ocean University of China, China

    4 publications · 74 citations

    4

    h-index

  4. BS
    Beatriz Salesa

    Valencia Catholic University Saint Vincent Martyr, Spain

    3 publications · 93 citations

    3

    h-index

  5. ÁS
    Ángel Serrano‐Aroca

    Valencia Catholic University Saint Vincent Martyr, Spain

    3 publications · 93 citations

    3

    h-index

1–5 of 912

Institutions

330

  1. King Saud University

    Riyadh, Saudi Arabia

    6 h-index

    16 publications

    683 citations

  2. University of Nottingham

    Nottingham, United Kingdom

    5 h-index

    16 publications

    1K citations

  3. Queen's Medical Centre

    Nottingham, United Kingdom

    4 h-index

    15 publications

    977 citations

  4. Ocean University of China

    Qingdao, China

    4 h-index

    16 publications

    315 citations

  5. University of Pisa

    Pisa, Italy

    3 h-index

    13 publications

    199 citations

  6. Valencia Catholic University Saint Vincent Martyr

    Valencia, Spain

    3 h-index

    6 publications

    186 citations

  7. Fund for the Replacement of Animals in Medical Experiments

    Nottingham, United Kingdom

    2 h-index

    2 publications

    114 citations

  8. National Research Council Canada

    Ottawa, Canada

    2 h-index

    6 publications

    816 citations

1–8 of 330

Venues

  1. PubMed

    Repository · 15 publications · 656 citations

    13

    h-index

  2. Toxicology in Vitro

    8 publications · 578 citations

    8

    h-index

  3. Molecules

    5 publications · 185 citations

    5

    h-index

  4. Asian Pacific Journal of Cancer Prevention

    APJCP · 5 publications · 299 citations

    5

    h-index

  5. Alternatives to Laboratory Animals

    4 publications · 138 citations

    4

    h-index

1–5