Transductional Efficacy and Safety of an Intraperitoneally Delivered Adenovirus Encoding an Anti-erbB-2 Intracellular Single-Chain Antibody for Ovarian Cancer Gene Therapy

Studies of the HER-2/ <i>neu</i> Proto-Oncogene in Human Breast and Ovarian Cancer

Dennis J. Slamon, William Godolphin, Lovell A. Jones et al. · Science · 1989 · 6.9K citations

Medicine, Molecular Biology, Oncology +15

Widespread long-term gene transfer to mouse skeletal muscles and heart.

Leslie D. Stratford-Perricaudet, Iman Makeh, Michel Perricaudet et al. · Journal of Clinical Investigation · 1992 · 584 citations · Full text

Pharmacy, Biotechnology, Genetics +16

Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells.

Richard J. Pietras, B M Fendly, V R Chazin et al. · PubMed · 1994 · 438 citations

Medicine, Molecular Biology, Oncology +12

Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies

Jeffrey A. Drebin, Victoria C. Link, David F. Stern et al. · Cell · 1985 · 404 citations

Medicine, Molecular Biology, Oncology +12

Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component.

Richard G. Vile, J. Arly Nelson, Simon Castleden et al. · PubMed · 1994 · 310 citations

Medicine, Immunology, Oncology +15