Concepedia

Publication | Open Access

Release of HMGB1 in Response to Proapoptotic Glioma Killing Strategies: Efficacy and Neurotoxicity

DOIFull Paper Access

104

Citations

52

References

2009

Year

Marianela Candolfi, Kader Yagiz, David Foulad, Gabrielle E. Alzadeh, Matthew Tesarfreund, A.K.M. Ghulam Muhammad, Mariana Puntel, Kurt M. Kroeger, Chunyan Liu, Sharon Lee,
Clinical Cancer Research

Abstract

Our results indicate that Ad-TK+GCV+Ad-Flt3L exhibit the highest efficacy and safety profile among the several proapoptotic approaches tested. The results reported further support the implementation of this combined approach in a phase I clinical trial for GBM.

References

YearCitations

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