The Journal of Organic Chemistry · 2012 · 77 citations · 34 references
Natural SciencesChemistryMedicinal ChemistryDrug DiscoveryOrganic ChemistryOrganometallic ChemistryHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsOrganic SynthesisStereoselective Synthesis
The electrophilic cyclization of 2-(1-alkynyl)benzamides affords high yields of cyclic imidates, instead of the previously reported isoindolin-1-ones, where cyclization proceeds on the oxygen of the carbonyl group rather than the nitrogen of the amide functionality. X-ray crystallography and spectroscopic techniques have been used to characterize the products. A correction is hereby provided in order to rectify the previous misassignment of structure.
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Dawei Yue, Tuanli Yao, Richard C. Larock · The Journal of Organic Chemistry · 2005 · 308 citations · Full text
José Barluenga, Mónica Trincado, Eduardo Rubio et al. · Angewandte Chemie International Edition · 2003 · 299 citations · Full text