Histamine and VIP interactions with receptor-cyclic AMP systems in the human gastric cancer cell line HGT-1

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Definition and Antagonism of Histamine H2-receptors

J. W. Black, W. A. M. Duncan, C. J. DURANT et al. · Nature · 1972 · 2.3K citations

Medicine, Medicinal Chemistry, Pharmacology +12

Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

Steven Collins, Robert C. Gallo, Robert E. Gallagher · Nature · 1977 · 2.1K citations

Life Sciences, Cell Biology, Hematology +16

Physiology of the Gastrointestinal Tract.

Annals of Internal Medicine · 1982 · 2K citations

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The Fluorometric Measurement of Deoxyribonucleic Acid in Animal Tissues with Special Reference to the Central Nervous System

John M. Kissane, Eli Robins · Journal of Biological Chemistry · 1958 · 1.8K citations · Full text

Life Sciences, Molecular Biology, Neuroscience +16