Palladium-Catalyzed Three-Component Arylcyanation of Internal Alkynes with Aryl Bromides and K₄[Fe(CN)₆]

Abstract

The one-pot, palladium-catalyzed, three-component coupling of aryl bromides, internal alkynes, and environmentally friendly K4[Fe(CN)6] provides an efficient and direct method for the preparation of beta-arylalkenylnitriles.