Journal of Biomedical Materials Research Part A · 2009 · 53 citations · 39 references
EngineeringMaterials ScienceOrthopedic SurgeryBiomaterialsBone GraftingTissue EngineeringBone Graft MaterialsBone Graft SubstitutesBone Tissue EngineeringScaffold DesignScaffold FabricationTissue Engineering ScaffoldsBiomaterial ScaffoldsBone Mechanical PropertiesDental ImplantsFiber OrientationOrthopedic ImplantsPorosityPorous ScaffoldsScaffold Architecture
3D porous Ti6Al4V scaffolds were directly fabricated by a rapid prototyping technology, 3D fiber deposition (3DF). In this study, scaffolds with different structures were fabricated by changing fiber spacing and fiber orientation. The influence of different architectures on mechanical properties and permeability of the scaffold were investigated. Mechanical analysis revealed that compressive strength and E-modulus increase with decreasing the porosity. Permeability measurements showed that not only the total porosity but also the porous structure can influence the permeability. 3DF was found to provide good control and reproducibility of the desired degree of porosity and the 3D structure. Results of this study demonstrate that the 3DF of Ti6Al4V give us flexibility and versatility to fabricate and improve scaffolds to better mimic the architecture and properties of natural bone and meet the requirements of bone graft substitutes and orthopedic and dental implants.
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Scaffolds in tissue engineering bone and cartilage
Dietmar W. Hutmacher · Biomaterials · 2000 · 4.9K citations
Dietmar W. Hutmacher, Thorsten Schantz, Iwan Zein et al. · Journal of Biomedical Materials Research · 2001 · 1.4K citations
Three‐dimensional printing of porous ceramic scaffolds for bone tissue engineering
Hermann Seitz, Wolfgang Rieder, Stephan Irsen et al. · Journal of Biomedical Materials Research Part B Applied Biomaterials · 2005 · 734 citations · Full text
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W. Pompe, H. Worch, Matthias Epple et al. · Materials Science and Engineering A · 2003 · 571 citations
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