Reaction of Cα,<i>O</i>‐dilithiooximes with functionalized carbonyl compounds. Part <b>2</b>. Reaction with α‐chloroketones and α,β‐unsaturated aldehydes and ketones

Abstract

Abstract The reaction of Cα,O ‐Dilithiooximes 2 and α‐chloroketones afforded 5‐(hydroxymethyl)‐Δ 2 ‐soxazolines 4 . α,β ‐Unsaturated aldehydes and ketones reacted with 2 to give the corresponding acyclic 1,2‐addition products 5 . The latter were cyclized with phosphorus pentoxide to 5‐vinyl‐Δ 2 ‐isoxazolines 6 .