Yellow Palms and Soles in Diabetes Mellitus

Abstract

A 55-year-old man presented with a 1-month history of yellow discoloration of his palms and soles (arrow, right palm, as compared with a normal palm to the left). Diabetes mellitus had been diagnosed 1 month before admission. His conjunctiva were not icteric. The fasting glucose level was 293 mg per deciliter (16.2 mmol per liter), and the glycated hemoglobin value was 12.8%. The serum bilirubin and free thyroxine levels were within normal limits. He did not report ingesting excessive amounts of carotene-rich fruits or vegetables, such as carrots, squash, and green beans. Yellow discoloration of the skin may be associated . . .