Transient Receptor Potential Channels Contribute to Pathological Structural and Functional Remodeling After Myocardial Infarction - Concepedia

Concepedia

Publication | Open Access

Transient Receptor Potential Channels Contribute to Pathological Structural and Functional Remodeling After Myocardial Infarction

DOI Full Paper Access

115

Citations

42

References

2014

Year

Catherine A. Makarewich, Hongyu Zhang, Jennifer Davis, Robert N. Correll, Danielle M. Trappanese, Nicholas E. Hoffman, Constantine D. Troupes, Remus M. Berretta, Hajime Kubo, Muniswamy Madesh,

Circulation Research

Abstract

Ca2+ influx through TRPC channels expressed after MI activates pathological cardiac hypertrophy and reduces contractility reserve. Blocking post-MI TRPC activity improved post-MI cardiac structure and function.

References

	Year	Citations

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