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On-column ligand synthesis coupled to partial-filling affinity capillary electrophoresis to estimate binding constants of ligands to a receptor

Capillary ElectrophoresisBiochemistryMedicineNatural SciencesBioanalysisPharmacologyReceptor (Biochemistry)Non-peptide LigandMolecular RecognitionMolecular DockingMolecular ModelingSmall MoleculesDrug DiscoveryOn-column Ligand Synthesis