Hypoxia-induced cell death and changes in hypoxia-inducible factor-1 activity in PC12 cells upon exposure to nerve growth factor

Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

Peter Carmeliet, Yuval Dor, Jean-Marc Herbert et al. · Nature · 1998 · 2.5K citations

Medicine, Cancer Biology, Cell Biology +16

Cellular and developmental control of O₂ homeostasis by hypoxia-inducible factor 1α

Narayan V. Iyer, Lori E. Kotch, Faton Agani et al. · Genes & Development · 1998 · 2.5K citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +16

HIF‐1α is required for solid tumor formation and embryonic vascularization

Heather E. Ryan · The EMBO Journal · 1998 · 1.6K citations · Full text

Medicine, Developmental Biology, Oncology +14

An essential role for p300/CBP in the cellular response to hypoxia

Zoltàn Arany, Eric Huang, Richard Eckner et al. · Proceedings of the National Academy of Sciences · 1996 · 798 citations

Life Sciences, Cell Biology, Molecular Biology +14

Regulation of the Hypoxia-inducible Transcription Factor 1α by the Ubiquitin-Proteasome Pathway

Pekka Kallio, W.J. Wilson, Sallyann L. O’Brien et al. · Journal of Biological Chemistry · 1999 · 747 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16