Synthetic Communications · 2001 · 28 citations · 13 references
Natural SciencesChemical EngineeringChemistryIndustrial ChemistryReaction EngineeringBiodegradationDegradation ProductsReactive Oxygen SpeciesSafer Chemical SynthesisOxidative Degradation ProductsWaste-minimized Synthesis
The commercial synthesis of Ambrox® is modified so that the key intermediate, the sclareolide, results from an indirect oxidative degradation of sclareol. This method allows to greatly alleviate the waste disposal problem and to raise the overall yield of Ambrox® to 75%.
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