Spatially and Functionally Distinct Roles of the PI3-K Effector Pathway during NGF Signaling in Sympathetic Neurons

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Chris J. Vlahos, William F. Matter, K. Y. Hui et al. · Journal of Biological Chemistry · 1994 · 3.2K citations · Full text

Specific Inhibitor, Molecular Pharmacology, Medicinal Chemistry +16

Requirement for Phosphatidylinositol-3 Kinase in the Prevention of Apoptosis by Nerve Growth Factor

Ryoji Yao, Geoffrey M. Cooper · Science · 1995 · 1.4K citations

Apoptosis, Cell Death, Cell Proliferation +17

Local control of neurite development by nerve growth factor

Robert B. Campenot · Proceedings of the National Academy of Sciences · 1977 · 739 citations · Full text

Neuroregeneration, Developmental Biology, Neurophysiology +15

Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase.

Garth Powis, Rosanne Bonjouklian, Margareta Berggren et al. · PubMed · 1994 · 691 citations

Tyrosine Kinase, Cellular Pharmacology, Cellular Physiology +17

The retrograde axonal transport of nerve growth factor

Ian A. Hendry, K. Sto ̈ckel, H. Thoenen et al. · Brain Research · 1974 · 602 citations

Neuroregeneration, Peripheral Nerve Injury, Neuroanatomy +7