Dual effect of p53 on radiation sensitivity in vivo: p53 promotes hematopoietic injury, but protects from gastro-intestinal syndrome in mice

<i>p53</i> Status and the Efficacy of Cancer Therapy in Vivo

Scott W. Lowe, Stephan Bodis, Andrea I. McClatchey et al. · Science · 1994 · 1.5K citations

Medicine, Cancer Biology, Oncology +17

A Chemical Inhibitor of p53 That Protects Mice from the Side Effects of Cancer Therapy

Pavel G. Komarov, Elena A. Komarova, Roman V. Kondratov et al. · Science · 1999 · 1.3K citations

Medicine, Oncology, Pharmacology +17

Endothelial Apoptosis as the Primary Lesion Initiating Intestinal Radiation Damage in Mice

François Paris, Zvi Fuks, Anthony D. Kang et al. · Science · 2001 · 1.3K citations

Medicine, Oncology, Radiation Oncology +17

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide

Carsten Culmsee, Xiaoxiang Zhu, Qian‐sheng Yu et al. · Journal of Neurochemistry · 2001 · 316 citations

Life Sciences, Neuroscience, Pharmacology +17

atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity

Christoph Westphal, Sheldon Rowan, Cornelius Schmaltz et al. · Nature Genetics · 1997 · 227 citations

Medicine, Cancer Biology, Oncology +14