PLoS ONE · 2013 · 157 citations · 25 references
Veterinary MedicineInfectious DiseasesVeterinary MicrobiologyMedical MicrobiologySwine MedicineSwine ScienceLivestock Infectious DiseasesSwine DiseaseSwine EpidemiologySwine HealthSwine Infectious DiseasesSwine WelfareAntimicrobial Use In SwineLivestock-associated Methicillin-resistant Staphylococcus AureusPorcine Infectious DiseasesSpa TypingSwine Disease EpidemiologySwine Infectious Disease Epidemiology
Much uncertainty remains about the origin and public health implications of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA). This study aimed to investigate the occurrence and prevalence of MRSA in general and LA-MRSA in particular in pigs and farm workers in five states. We collected nasal swabs from pigs and farm workers at 45 swine herds (21 antibiotic-free herds; 24 conventional herds) in Illinois, Iowa, Minnesota, North Carolina and Ohio. MRSA was isolated from 50 of 1085 pigs (4.6%) and 31 of 148 (20.9%) of farm workers. MRSA-positive pigs and people were clustered in four conventional swine farms in Iowa and Illinois. Based on genotyping, spa type t034, a common livestock associated variant, was predominant among both human and swine isolates. These results confirm the presence of LA-MRSA in pigs and swine farm workers in the USA, but the prevalence found is relatively low compared with European studies.
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Staphylococcus aureus CC398: Host Adaptation and Emergence of Methicillin Resistance in Livestock
Lance B. Price, Marc Stegger, Henrik Hasman et al. · mBio · 2012 · 851 citations · Full text
Larry Koreen, Srinivas V. Ramaswamy, Edward A. Graviss et al. · Journal of Clinical Microbiology · 2004 · 485 citations · Full text