Risk Factors for Developing Tuberculosis in HIV-1–Infected Adults From Communities With a Low or Very High Incidence of Tuberculosis

Abstract

HIV-infected adults in Cape Town are at high risk of developing tuberculosis irrespective of tuberculin skin testing. The risk increases markedly with HIV disease progression. Patients at extremely high risk can be identified on the basis of demographic and clinical features. Such individuals would be suitable for targeted tuberculosis prophylaxis.