Archives of Internal Medicine · 2003 · 164 citations · 16 references
Air travel is a mild risk factor for venous thromboembolism, doubling the risk of the disease. When thrombophilia or oral contraceptive use is present, the risk increases to 16-fold and 14-fold, respectively, indicating a multiplicative interaction.
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Severe Pulmonary Embolism Associated with Air Travel
Frédéric Lapostolle, Vanessa Surget, Stephen W. Borron et al. · New England Journal of Medicine · 2001 · 402 citations · Full text