The stereospecific synthesis of a carbacyclin analogue using the protodesilylation of an allylsilane

Prostaglandin analogs. Part 9. Synthesis of a new chemically and metabolically stable prostacyclin analog with high and long-lasting oral activity

Werner Skuballa, E. Schillinger, C.‐ST. STUERZEBECHER et al. · Journal of Medicinal Chemistry · 1986 · 117 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Nickel-catalyzed cross-couplings of alkenyl and .alpha.-metalated alkenyl sulfoximines with organometallics. Stereoselective synthesis of carbacyclins

Irène Erdelmeier, Hans Joachim Gais · Journal of the American Chemical Society · 1989 · 94 citations

Natural Sciences, Chemistry, Catalysis +11

Synthesis via vinyl sulfones. 22. A chemodirected, triply-convergent total synthesis of d-(+)-carbacyclin

D. K. HUTCHINSON, P. L. Fuchs · Journal of the American Chemical Society · 1987 · 58 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Total synthesis of 6a-carbaprostaglandin I2 and related isomers

Douglas R. Morton, Frances C. Brokaw · The Journal of Organic Chemistry · 1979 · 55 citations

Natural Sciences, Chemistry, Pharmacology +8

Total synthesis of carboprostacyclin, a stable and biologically active analogue of prostacyclin (PGI2)

K. C. Nicolaou, W. J. Sipio, Ronald L. Magolda et al. · Journal of the Chemical Society Chemical Communications · 1978 · 51 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9