Immune responses after immunization with plasmid DNA encoding Bet v 1, the major allergen of birch pollen

CpG motifs in bacterial DNA trigger direct B-cell activation

Arthur Μ. Krieg, Ae‐Kyung Yi, Sara Matson et al. · Nature · 1995 · 3.5K citations

Natural Sciences, Virulence Factor, Cpg Motifs +4

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

Jeffrey B. Ulmer, John Donnelly, Suezanne E. Parker et al. · Science · 1993 · 2.3K citations

Vaccination, Cross-protection, Viral Protein +14

Genetic immunization is a simple method for eliciting an immune response

De‐chu C. Tang, Michael J. DeVit, Stephen Albert Johnston · Nature · 1992 · 1.5K citations

Vaccination, Autoimmune Disease, Allergy +12

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.

Dennis M. Klinman, Ae‐Kyung Yi, Serge L. Beaucage et al. · Proceedings of the National Academy of Sciences · 1996 · 1.5K citations · Full text

Innate Immune System, Bacteriology, Immunology +18

Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization

Yukio Sato, Mark Roman, Helen Tighe et al. · Science · 1996 · 1.1K citations

Immunogenetics, Autoimmune Disease, Allergy +14