Indian Journal of Medical Microbiology · 2012 · 10 citations · 8 references
DentistryMicrobiologyOral BiologyMetagenomicsMicrobiome ResearchOral MicrobiologyDental PlaqueMicrobiological AnalysisOral Bacterial EcologyOral MicrobiomePeriodontal MicrobiologyPeriodontal MicrobiomeLaboratory InvestigationsMetagenomic Diversity AnalysisOral Commensal BacteriaOral Microbiome AnalysisOral Microbiome In DiseaseOral Microbiome MetagenomicsOral Microbiome ProfilingSingle-strand Conformation Polymorphism
To address the question if an altered oral microbiota is associated with atherosclerosis. Twenty patients suffering from atherosclerosis and 10 controls were recruited. Clinical oral, medical and laboratory investigations were performed. Oral bacteria were collected and 16S rDNA was sequenced following Single strand conformation polymorphism.(SSCP) Probing pocket depths in patients were significantly elevated. The oral microbiota of patients and controls were dominated by Fusobacterium (16%/17%), Streptococcus (21%/14%), Prevotella (10%/12%), Enterococcus (12%/12%), Porphyromonas (8%/7%), TM7 (0%/7%) and Veillonella (6%/7%). Differences in diversity were not significant between groups. The pathology of atherosclerosis may not be related to significant qualitative changes of the oral microbiota.
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Human oral, gut, and plaque microbiota in patients with atherosclerosis
Omry Koren, Aymé Spor, Jenny Felin et al. · Proceedings of the National Academy of Sciences · 2010 · 1.2K citations
Epidemiology of periodontal diseases: an update.
Panos N. Papapanou · PubMed · 1999 · 175 citations