Critical role for the catalytic activity of phospholipase C-γ1 in epidermal growth factor-induced cell migration

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils.

John E. Bleasdale, Nirja Thakur, R S Gremban et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 632 citations

Medicine, Cell Biology, Pharmacology +17

Receptor-coupled signal transduction in human polymorphonuclear neutrophils: effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness.

Robert J. Smith, Laurel M. Sam, J M Justen et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 573 citations

Life Sciences, Immunology, Pharmacology +14

Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement.

P Chen, Haihua Xie, Mahendran Sekar et al. · The Journal of Cell Biology · 1994 · 328 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

ICAM-1-Coupled Cytoskeletal Rearrangements and Transendothelial Lymphocyte Migration Involve Intracellular Calcium Signaling in Brain Endothelial Cell Lines

Sandrine Etienne‐Manneville, Jean‐Baptiste Manneville, Peter Adamson et al. · The Journal of Immunology · 2000 · 295 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17