New Moloka'iamine Derivatives from an Undescribed Verongid Sponge

Abstract

The polar extract of an undescribed Verongid sponge from the island of Molokai yielded three new bromotyramines. Two compounds terminate in a chlorocyclopentanedione enamine moiety. Their structures were elucidated by NMR spectra measured at -30 degrees C. The third compound is the N-methyl derivative of a known compound. This structure was determined by NMR spectra measured at room temperature.