The CaV1.4 Calcium Channel Is a Critical Regulator of T Cell Receptor Signaling and Naive T Cell Homeostasis

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

Ole Thastrup, Peter J. Cullen, Bjørn K. Drøbak et al. · Proceedings of the National Academy of Sciences · 1990 · 3.3K citations

Life Sciences, Cell Biology, Pharmacology +15

An L-type calcium-channel gene mutated in incomplete X-linked congenital stationary night blindness

Tim M. Strom, Gerald Nyakatura, Eckart Apfelstedt-Sylla et al. · Nature Genetics · 1998 · 504 citations

Life Sciences, Genetics, Molecular Genetics +12

Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release–activated calcium channels

Monika Vig, Wayne I. DeHaven, Gary S. Bird et al. · Nature Immunology · 2007 · 396 citations

Life Sciences, Immunology, Physiology +17

Mutation of the Ca2+ Channel β Subunit Gene Cchb4 Is Associated with Ataxia and Seizures in the Lethargic (lh) Mouse

Daniel L. Burgess, Julie Miller Jones, Miriam H. Meisler et al. · Cell · 1997 · 395 citations · Full text

Life Sciences, Genetics, Neuroscience +9

T Cell Receptor–initiated Calcium Release Is Uncoupled from Capacitative Calcium Entry in Itk-deficient T Cells

Karen‐Qianye Liu, Stephen C. Bunnell, Christine B. Gurniak et al. · The Journal of Experimental Medicine · 1998 · 335 citations · Full text

Life Sciences, Biochemistry, Immunology +16