An early requirement for nkx2.5 ensures the first and second heart field ventricular identity and cardiac function into adulthood

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Kristen M. Kwan, E. Fujimoto, Clemens Grabher et al. · Developmental Dynamics · 2007 · 1.9K citations

Life Sciences, Biotechnology, Genetics +15

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

Lei Yang, Mark H. Soonpaa, Eric Adler et al. · Nature · 2008 · 1.4K citations · Full text

Life Sciences, Cell Biology, Developmental Biology +14

Congenital Heart Disease Caused by Mutations in the Transcription Factor <i>NKX2-5</i>

Jean‐Jacques Schott, D. Woodrow Benson, Craig T. Basson et al. · Science · 1998 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +17

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5.

Ian Lyons, Linda M. Parsons, Lynne Hartley et al. · Genes & Development · 1995 · 1.1K citations · Full text

Life Sciences, Developmental Biology, Genetics +15

The gene <i>tinman</i> is required for specification of the heart and visceral muscles in <i>Drosophila</i>

Rolf Bodmer · Development · 1993 · 797 citations

Life Sciences, Biology, Developmental Biology +17