Regulation of the Human Corticotropin-Releasing-Hormone Gene Promoter Activity by Antidepressant Drugs in Neuro-2A and AtT-20 Cells

Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients

Charles B. Nemeroff, Erik Widerlöv, Garth Bissette et al. · Science · 1984 · 1.5K citations

Life Sciences, Neuroscience, Psychiatry +17

Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus

Masashi Nibuya, EJ Nestler, R. S. Duman · Journal of Neuroscience · 1996 · 1.2K citations · Full text

Life Sciences, Neuroscience, Pharmacology +15

Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated

Astrid Zobel, Thomas Nickel, Heike Künzel et al. · Journal of Psychiatric Research · 2000 · 704 citations

Medicine, Pharmacology, Psychiatry +14

Increased Numbers of Corticotropin-Releasing Hormone Expressing Neurons in the Hypothalamic Paraventricular Nucleus of Depressed Patients

F.C. Raadsheer, Witte J.G. Hoogendijk, Frans C. Stam et al. · Neuroendocrinology · 2008 · 662 citations · Full text

Life Sciences, Neuroscience, Psychiatry +17

On the Role of Brain Mineralocorticoid (Type I) and Glucocorticoid (Type II) Receptors in Neuroendocrine Regulation

Anna Ratka, Winardi Sutanto, Margreet Bloemers et al. · Neuroendocrinology · 2008 · 479 citations

Medicine, Endocrinology, Pharmacology +16