FK 506 and Rapamycin in Combination Are Not Antagonistic but Produce Extended Small Bowel Graft Survival in the Mouse

FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro.

Toru Kino, Hiroshi Hatanaka, Susumu Miyata et al. · The Journal of Antibiotics · 1987 · 1.2K citations · Full text

Medicine and the Law

Diana Brahams · The Lancet · 1987 · 537 citations

Philosophy Of Medicine, Medical Ethics, Medical Law +4

Successful small-bowel/liver transplantation

David Grant, William Wall, Richard Mimeault et al. · The Lancet · 1990 · 455 citations

Transplantation Surgery, Successful Small-bowel/liver Transplantation, Intestinal Transplantation +8

Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation.

S Sawada, Gen Suzuki, Yoshiko Kawase et al. · The Journal of Immunology · 1987 · 417 citations · Full text

Immune Regulation, Immunology, Cyclosporin A +16

The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells.

Francis J. Dumont, Michael Melino, Mary Jo Staruch et al. · The Journal of Immunology · 1990 · 355 citations · Full text