A Novel Role for the Major Histocompatibility Complex Class II Transactivator CIITA in the Repression of IL-4 Production

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

Timothy R. Mosmann, Holly Cherwinski, M W Bond et al. · The Journal of Immunology · 1986 · 7.5K citations

Adaptive Immune System, T-regulatory Cell, Cellular Immunology +19

The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

Wei-ping Zheng, Richard A. Flavell · Cell · 1997 · 2.3K citations · Full text

Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells

Mark H. Kaplan, Ulrike Schindler, Stephen T. Smiley et al. · Immunity · 1996 · 1.6K citations · Full text

Inflammation, Cytokine, Th2 Cells +10

Essential role of Stat6 in IL-4 signalling

Takashi Tanaka, Wei Shi, Makoto Matsumoto et al. · Nature · 1996 · 1.6K citations

Inflammation, Cytokine, Autoimmune Disease +7

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene

Kazuya Shimoda, Jan van Deursent, Mark Y. Sangster et al. · Nature · 1996 · 1.3K citations

Inflammation, Immunogenetics, Il-4-induced Th2 Response +10