Conformational Transitions Underlying Pore Opening and Desensitization in Membrane-embedded Gloeobacter violaceus Ligand-gated Ion Channel (GLIC)

A study of the ‘desensitization’ produced by acetylcholine at the motor end‐plate

B. Katz, S. Thesleff · The Journal of Physiology · 1957 · 1.5K citations · Full text

‘ Desensitization ’, Motor End‐plate, Neurophysiology +9

Principles of activation and permeation in an anion-selective Cys-loop receptor

Ryan Hibbs, Eric Gouaux · Nature · 2011 · 981 citations

Molecular Pharmacology, Anion-selective Cys-loop Receptor, Signal Transduction +8

Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons

Clay M. Armstrong · The Journal of General Physiology · 1971 · 935 citations · Full text

Biochemistry, Hyperpolarization (Biology), Potassium Conductance +13

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

Keiji Imoto, Christopher Büsch, Bert Sakmann et al. · Nature · 1988 · 792 citations

Molecular Physiology, Amino Acids, Biochemistry +9

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

Nicolas Bocquet, Hugues Nury, Marc Baaden et al. · Nature · 2008 · 668 citations · Full text

X-ray Crystallography, X-ray Structure, Natural Sciences +10