Current Chemical Biology · 2009 · 23 citations · 45 references
Life SciencesBiochemistryMolecular BiologyCarbohydrate ChemistryEnzymologyGlycobiologyCarbohydrate StructureGlycan StructureMonosaccharide ChemistryMonosaccharide StructureN-linked GlycosylationPolysaccharide StructureOligosaccharide CharacterizationOligosaccharide StructureOligosaccharide Synthesis
This review will describe the recent advances in the field of oligosaccharides containing at least one unit of a polyhydroxylated piperidine or pyrrolidine. The review will cover both chemical and biological aspects concerning their preparation and/or occurrence in Nature as well as their biological properties which include glycosylase, and glycosyl transferase inhibition, among others. These enzymatic inhibitory properties are the basis for the potential use of the title compounds in viral infections, cancer and genetic disorders. Keywords: Iminosugars, oligosaccharides, glycosidase inhibitors, azasugars, piperidines
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N-containing sugars fromMorus alba and their glycosidase inhibitory activities
Naoki Asano, Kengo Oseki, Emiko Tomioka et al. · Carbohydrate Research · 1994 · 275 citations