Differentiation of Subvisible Silicone Oil Droplets from Irregular Standard Dust Particles

Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine

M H Zweig, Gregory Campbell · Clinical Chemistry · 1993 · 6.6K citations

Public Health, Biostatistics, Clinical Sciences +16

Overlooking Subvisible Particles in Therapeutic Protein Products: Gaps That May Compromise Product Quality

John F. Carpenter, Theodore W. Randolph, Wim Jiskoot et al. · Journal of Pharmaceutical Sciences · 2008 · 588 citations · Full text

Life Sciences, Biochemistry, Pharmaceutics +16

Silicone Oil- and Agitation-Induced Aggregation of a Monoclonal Antibody in Aqueous Solution

Renuka Thirumangalathu, Sampathkumar Krishnan, Margaret Speed Ricci et al. · Journal of Pharmaceutical Sciences · 2009 · 289 citations · Full text

Pharmacy, Biochemistry, Immunology +9

Micro-Flow Imaging: Flow Microscopy Applied to Sub-visible Particulate Analysis in Protein Formulations

Deepak K. Sharma, D. Tommy King, Peter Oma et al. · The AAPS Journal · 2010 · 181 citations · Full text

Engineering, Biochemistry, Pharmaceutical Analysis +10

Discrimination Between Silicone Oil Droplets and Protein Aggregates in Biopharmaceuticals: A Novel Multiparametric Image Filter for Sub-visible Particles in Microflow Imaging Analysis

René Strehl, Verena Rombach‐Riegraf, Manuel Diez et al. · Pharmaceutical Research · 2011 · 117 citations

Engineering, Biomedical Engineering, Pharmaceutical Analysis +16