Interleukin-2 gene-modified allogeneic melanoma cell vaccines can induce cross-protection against syngeneic tumors in mice

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

Glen Dranoff, Elizabeth M. Jaffee, A Lazenby et al. · Proceedings of the National Academy of Sciences · 1993 · 2.8K citations

Medicine, Immunology, Oncology +17

Role of Bone Marrow-Derived Cells in Presenting MHC Class I-Restricted Tumor Antigens

Alex Y. Huang, Paul T. Golumbek, Mojgan Ahmadzadeh et al. · Science · 1994 · 1.2K citations

Life Sciences, Immunology, Oncology +17

Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor.

Yutaka Kawakami, S Eliyahu, C H Delgado et al. · Proceedings of the National Academy of Sciences · 1994 · 1.1K citations

Life Sciences, Immunology, Molecular Biology +17

Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

Eric R. Fearon, Drew M. Pardoll, Toshiuki Itaya et al. · Cell · 1990 · 922 citations

Life Sciences, Immunology, Oncology +17

Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes.

Béatrice Gaugler, Benoı̂t Van den Eynde, Pierre van der Bruggen et al. · The Journal of Experimental Medicine · 1994 · 765 citations · Full text

Life Sciences, Immunology, Molecular Biology +17