Concepedia

Platelet 12-lipoxygenase Arg261Gln polymorphism: functional characterization and association with risk of esophageal squamous cell carcinoma in combination with COX-2 polymorphisms

Yongli Guo, Xuemei Zhang, Wen Tan, Xiaoping Miao, Tong Sun, Dan Zhao, Dongxin Lin

Pharmacogenetics and Genomics · 2007 · 42 citations · 53 references

DOI

Abstract

These observations suggest that inherited polymorphisms in arachidonic acid-metabolizing enzymes, which result in heightened gene expression or enzymatic activity, may confer host susceptibility to ESCC.

References

53

Major Causes of Death among Men and Women in China

Jiang He, Dongfeng Gu, Xigui Wu et al. · New England Journal of Medicine · 2005 · 1.1K citations

Population Attributable Risks of Esophageal and Gastric Cancers

Lawrence S. Engel, W.-H. Chow, Thomas L. Vaughan et al. · JNCI Journal of the National Cancer Institute · 2003 · 787 citations · Full text

Cyclooxygenase-2 expression in human esophageal carcinoma.

Katja Zimmermann, Mario Sarbia, Artur‐Aron Weber et al. · PubMed · 1999 · 669 citations

, , +11

Nutrition Intervention Trials in Linxian, China: Multiple Vitamin/Mineral Supplementation, Cancer Incidence, and Disease-Specific Mortality Among Adults With Esophageal Dysplasia

Jingyuan Li, Philip R. Taylor, Bin Li et al. · JNCI Journal of the National Cancer Institute · 1993 · 427 citations

Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis.

Dean G. Tang, Yong Q. Chen, Kenneth V. Honn · Proceedings of the National Academy of Sciences · 1996 · 336 citations · Full text

, , +19